Mathieu Bourguignon

Mathieu Bourguignon

Lecture 1: From MEG signals to functional connectivity

Lecture 2: insights into human sensorimotor functions from MEG and coherence analysis

Firstly, functional connectivity is introduced with some illustrative examples of how the brain is organised, according to functional segregation and functional integration, how to define each, and we should study both. Secondly, the topic narrows to cortical activity measures with MEG, reflecting communication between the brain activity and the periphery, so-called cortico-kinematic coherence. Thirdly, cortico-kinematic coherence in the context of movement observation is addressed.


Cortico-kinematic coherence (CKC) is addressed as the coupling between hand kinematics and brain signals. After a brief introduction to the sensorimotor system, the study aims to better understand the brain network responsible for such coherence. The conclusion points towards proprioceptive feedback integration as the origin of CKC. Regarding its clinical possibilities, CKC method is successful but artefacts are especially limiting in the analysis.